Publications by authors named "M Cadei"

Background: Inflammatory bowel disease (IBD) includes Crohn's Disease (CD) and Ulcerative Colitis (UC). Correct diagnosis requires the identification of precise morphological features such basal plasmacytosis. However, histopathological interpretation can be challenging, and it is subject to high variability.

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Article Synopsis
  • Mucosal Melanomas (MM) are super aggressive cancers that arise in certain skin cells, and current treatments aren't helping much for advanced cases.
  • Scientists created five new cell lines (named SN-MM1-5) from patient samples to better study and understand these cancers, testing how they behave in lab experiments and in mice.
  • The study found that these new cell lines showed important differences from normal cells and identified specific cancer-related features, helping researchers learn more about how to treat mucosal melanomas better.
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Objective: The use of standardized structured reports (SSR) and suitable terminologies like SNOMED-CT can enhance data retrieval and analysis, fostering large-scale studies and collaboration. However, the still large prevalence of narrative reports in our laboratories warrants alternative and automated labeling approaches. In this project, natural language processing (NLP) methods were used to associate SNOMED-CT codes to structured and unstructured reports from an Italian Digital Pathology Department.

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Gallbladder cancer (GBC) is one of the deadliest malignancy and treatment options are deplorably limited. Better strategies of prevention are urgently needed but knowledge on risk factors remains scarce. Recent data suggested that arsenic (As) may be involved in GBC carcinogenesis but the question remains debated.

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