Publications by authors named "M Cadd"

Article Synopsis
  • * A systematic review and meta-analysis of 263 patients revealed no significant difference in vasopressor requirements, but hydroxocobalamin improved mean arterial pressure and reduced total vasopressor doses at 1 and 6 hours.
  • * The results suggest hydroxocobalamin is more effective than methylene blue for improving hemodynamics, but more high-quality research is needed to confirm these findings.
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Introduction: Hypoxic-ischaemic brain injury (HIBI), is a common sequalae following out-of-hospital cardiac arrest (OOHCA), it is reported as the cause of death in 68% of patients who survive to ICU admission, while other patients can be left with permanent neurological disability. Prediction of neurological outcome follows a multimodal approach, including use of the biomarker, neurone specific enolase (NSE). There is however no definitive cut-off value for poor neurological outcome, and little research has analysed NSE and long-term outcomes in survivors.

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Background: Pruritus is a frequently reported and unpleasant side effect following intrathecal opioid use with frequency further increased among parturients. We have performed a systematic review to assess the overall efficacy of ondansetron for the prevention of pruritus in patients receiving intrathecal opioid as part of spinal anesthesia for cesarean delivery.

Methods: A literature search of MEDLINE, Embase, Cochrane, and Web of Science databases was conducted from date of inception to September 2022.

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