Publications by authors named "M Cabre"
Objectives: Knowledge of frailty prevalence and incidence trends over time is essential for planning the necessary health and social resources. The objective of this study was to assess frailty prevalence, incidence, reversibility and mortality rates, and trends for the population aged ≥65 years in Catalonia over the period 2017-2021.
Study Design: Longitudinal epidemiological study.
Correlative methods to characterize single entities by electrochemistry and microscopy/spectroscopy are increasingly needed to elucidate structure-function relationships of nanomaterials. However, the technical constraints often differ depending on the characterization techniques to be applied in combination. One of the cornerstones of correlative single-entity electrochemistry (SEE) is the substrate, which needs to achieve a high conductivity, low roughness, and electrochemical inertness.
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- The study focuses on Fmr1-knockout (KO) rats, which are used as a model for Fragile X Syndrome and autism spectrum disorder (ASD).
- Researchers examined the effects of chlorpyrifos (CPF), a pesticide linked to ASD, on both KO and wild-type rats by assessing metabolic changes in various brain regions and gut content at different postnatal days.
- The findings revealed specific metabolic variations in brain tissues related to genotype and CPF exposure, including alterations in key biomarkers and metabolites associated with gastrointestinal dysfunction, while gene expression changes were minimal.
Autism spectrum disorder (ASD) encompasses several neurodevelopmental conditions characterized by communication and social impairment, as well as repetitive patterns of behavior. However, it can co-occur with other mental conditions such as anxiety. The massive use of chlorpyrifos (CPF) has been linked to the increased prevalence of developmental disorders.
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