This study aims to provide an in-depth examination of the histological changes that occur during the repair of untreated bone fractures in avian species, correlating these microscopic alterations with gross anatomical characteristics observed during different tissue repair phases. A total of 93 bone fractures from different wild birds were analyzed and classified based on temporality (acute, subacute, and chronic) according to the color changes of the hematoma and morphology (open or closed; simple, comminuted, or greenstick fractures). From a microscopic standpoint, a strong correlation was observed between the temporal progression observed macroscopically and the histological changes evident in each temporal category.
View Article and Find Full Text PDFThe factors that determine the appearance of the different pathologic forms associated with bovine paratuberculosis are not fully understood, but new research suggests a critical role of innate immunity. Toll-like receptors (TLRs) trigger the recognition of invading pathogens by innate immune cells and the onset of specific immune responses. The aim of this work was to assess, immunohistochemically, the expression of TLR1, TLR2, TLR4, and TLR9 in intestinal samples of 20 cows showing different types of paratuberculous lesions: uninfected controls, focal lesions, paucibacillary, and multibacillary diffuse forms.
View Article and Find Full Text PDFParatuberculosis is a chronic granulomatous enteritis, caused by subspecies (), that affects ruminants worldwide. Vaccination has been considered the most cost-effective method for the control of this disease in infected dairy herds. However, currently available vaccines do not provide complete protection and interfere with the diagnosis of both paratuberculosis and bovine tuberculosis, limiting its use.
View Article and Find Full Text PDFParkinson's Disease (PD) is a progressive neurodegenerative condition associated with deficit in reaction time which can lead to falls, resulting in limited independence, diminished quality of life, heightened rates of institutionalization and increased healthcare costs. We aimed to examine the effects of an acupuncture protocol in motor time response after an auditory stimulus. : This study employed a case series design.
View Article and Find Full Text PDF