Publications by authors named "M CHABERT"
Rift Valley fever (RVF) is one of the major viral arthropod-borne diseases in Africa. In recent decades, RVF virus (RVFV), the causative agent of RVF, has been responsible for multiple outbreaks in West Africa with important consequences on human and animal health. In particular, an outbreak occurred in 2010 after heavy rains in the desertic region of Adrar, Mauritania.
View Article and Find Full Text PDFBackground: Dysphagia, particularly sarcopenic dysphagia, is frequent in frail older patients. Sarcopenic dysphagia is a swallowing disorder caused by sarcopenia, corresponding to a loss of muscle mass and strength. It frequently leads to inhalation and to the decrease of food intake, leading the patient to enter a vicious circle of chronic malnutrition and frailty.
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- Influenza A virus infection activates the NLRP3 inflammasome, leading to the release of the proinflammatory cytokine IL-1β from immune cells, which contributes to inflammation and fever.
- The contemporary PB1-F2 protein from certain IAV strains inhibits NLRP3 activation via a specific four-amino acid motif (TQGS) that affects the binding and localization of PB1-F2.
- Phylogenetic analysis indicates that this NLRP3 inhibitory motif is conserved across recent human-infecting IAV strains, providing insight into the molecular mechanisms of immune evasion by the virus.
Objective: Central pontine myelinolysis (CPM) is a rare demyelinating disease that affects the pons and which can cause extreme disabilities such as locked-in syndrome (LIS) in the initial phase. The aim of the study was to describe the evolution over a 12-month period of two patients with CPM causing an initial LIS.
Method: We retrospectively report the unexpected clinical outcome of these two patients in relation with the anatomical damages documented by brain MRI, associated with diffusion tensor imaging and reconstruction of corticospinal tracts in tractography.
Rift Valley fever virus (RVFV) is a pathogenic arthropod-borne virus that can cause serious illness in both ruminants and humans. The virus can be transmitted by an arthropod bite or contact with contaminated fluids or tissues. Two live-attenuated veterinary vaccines-the Smithburn (SB) and Clone 13 (Cl.
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