Geographic differences in the phenology of gonadal development and moult, but not of egg laying, are genetically based in a small songbird.

To forecast how fast populations can adapt to climate change, it is essential to determine the evolutionary potential of different life-cycle stages under selection. In birds, timing of gonadal development and moult are primarily regulated by photoperiod, while laying date is highly phenotypically plastic to temperature. We tested whether geographic variation in phenology of these life-cycle events between populations of great tits () has a genetic basis, indicating that contemporary genetic adaptation is possible.

A deep learning approach versus expert clinician panel in the classification of posterior circulation infarction.

Background: Posterior circulation infarction (POCI) is common. Imaging techniques such as non-contrast-CT (NCCT) and diffusion-weighted-magnetic-resonance-imaging commonly fail to detect hyperacute POCI. Studies suggest expert inspection of Computed Tomography Perfusion (CTP) improves diagnosis of POCI.

Novel Vascular Territory Mapping Algorithm as a Predictive Tool for Identification of Antegrade Flow in Middle Cerebral Artery Occlusion.

Background: Vascular territory mapping (VTM) software estimates which intracerebral vessel provides predominant arterial flow to a brain voxel. The presence of antegrade flow in the setting of acute middle cerebral artery (MCA) occlusion is associated with improved outcomes. We identify whether VTM software is a determinant of antegrade flow in patients with proximal MCA occlusion.

Moderate and Vigorous Physical Activity Intensity Cut-Points for Hip-, Wrist-, Thigh-, and Lower Back Worn Accelerometer in Very Old Adults.

Physical activity (PA) reduces the risk of negative mental and physical health outcomes in older adults. Traditionally, PA intensity is classified using METs, with 1 MET equal to 3.5 mL O·min·kg.