A Highly Linear Ultra-Low-Area-and-Power CMOS Voltage-Controlled Oscillator for Autonomous Microsystems.

Voltage-controlled oscillators (VCOs) can be an excellent means of converting a magnitude into a readable value. However, their design becomes a real challenge for power-and-area-constrained applications, especially when a linear response is required. This paper presents a VCO for smart dust systems fabricated by 65 nm technology.

Immunomodulatory effect of sp. in mononuclear cells extracted from the blood of rheumatoid arthritis patients.

Background: Pathophysiological mechanisms of rheumatoid arthritis arise because of a proinflammatory environment, generated by the interaction of autoreactive lymphocytes and proinflammatory mediators. Current strategies to mitigate the progression of the disease produce adverse effects, so there is a need for new therapeutic strategies and molecular targets to treat this disease. In this context, evidence suggests that scorpion venoms could modulate the immune response and some important cellular mechanisms of pharmacological interest.

Association between type of menopause and mild cognitive impairment: The REDLINC XII study.

Objective: To evaluate the association between type of menopause (spontaneous or surgical) and mild cognitive impairment (MCI).

Study Design: This study was a cross-sectional, observational, and sub-analytical investigation conducted within gynecological consultations across nine Latin American countries.

Method: We assessed sociodemographic, clinical, and anthropometric data, family history of dementia, and the presence of MCI using the Montreal Cognitive Assessment (MoCA) tool.

Evaluating the Efficacy of Infliximab in Inflammatory Bowel Disease: A Systematic Review of the Literature.

The introduction of steroid therapy in 1955 markedly decreased the mortality rate of severe ulcerative colitis (UC) from 24% in the placebo group to 7%, and it is currently less than 1% in specialist centers. Despite this advancement, the response of severe UC to steroids has stagnated over the past 50 years, with a high rate of colectomy persisting for severe to moderately severe cases. Infliximab (IFX) (Remicade, Centocor Inc.