Publications by authors named "M C Terek"
Objectives: Endometrial cancer (EC) is the most commonly diagnosed gynecological cancer. Endometrial hyperplasia (EH) is a more common diagnosis than EC. Endometrial hyperplasia is found in approximately 1.
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- Obesity is linked to higher mortality rates in ovarian cancer, with leptin, a hormone produced by fat tissue, playing a significant role in cancer development.
- The study explored how varying levels of leptin influence the growth of ovarian cancer cells (specifically OVCAR-3 and MDAH-2774), assessing cell viability and cytokine expression changes.
- Results showed that leptin promotes cell proliferation in both cancer lines, affecting various cytokines differently; for instance, IL-1 levels increased in OVCAR-3, while TGF-β increased in MDAH-2774 after leptin treatment.
Objective: Since the first days of organ transplantation, it has been accepted that solid transplant recipients have a high risk of developing cancer. Chronic immunosuppression and environmental factors play a role in cancer development in recipients. In the present study, we tried to evaluate the cumulative incidence of cervical dysplasia after renal transplantation, risk factors for disease development, and the time until high-grade dysplasia occurred.
View Article and Find Full Text PDFDo tumor-infiltrating lymphocytes really indicate favorable prognosis in epithelial ovarian cancer?
Eur J Obstet Gynecol Reprod Biol
August 2017
Objective: The aim of this study is to evaluate the impact of lymphocyte infiltration on prognostic parameters, recurrence and survival in ovarian cancer.
Study Design: Sixty-two patients who were primarily operated for epithelial ovarian carcinoma between 1997 and 2008 were included. CD3, CD4, CD8, CD20 and FoxP3 expressions were evaluated immunohistochemically on sections obtained from paraffin-embedded tissues.
Introduction: We compared the disease free-survival (DFS) and overall survival (OS) rates of patients with high-grade serous primary fallopian tube cancer (HG-sPFTC) and high-grade serous epithelial ovarian cancer (HG-sEOC).
Methods: 22 early-stage cancer patients (International Federation of Gynecology and Obstetrics (FIGO) stages I-II) with HG-sPFTC were retrospectively evaluated. In addition, 44 control patients diagnosed with HG-sEOC were matched to these patients with respect to tumor stage at diagnosis.