Publications by authors named "M C Siracusa"
Article Synopsis
- Recent advancements in the management of differentiated thyroid cancer (DTC) emphasize the importance of careful postoperative disease assessment to determine if iodine-131 therapy is needed and to tailor treatment goals accordingly (ablative, adjuvant, or therapeutic).
- A comprehensive review of the literature highlights that personalized risk-based approaches to iodine-131 therapy significantly enhance early disease staging and response assessment, particularly for metastatic DTC patients.
- Diagnostic and theragnostic uses of iodine isotopes are crucial for improving postoperative risk stratification and enabling more effective evaluation of patient responses to initial treatments.
Radioligand therapy with [Lu]Lu-PSMA is a theranostic approach for heavily treated mCRPC patients with positive PSMA PET in the absence of relevant PSMA-negative metastases assessed through CT, MRI, bone scan or FDG PET. In this case, we described a mCRPC patient treated with RLT with discordant PSA values and PSMA images, in which Choline PET confirmed a biochemically suspected disease progression (PD), showing metastatic lesions not revealed by PSMA imaging.
View Article and Find Full Text PDFThis study investigated the concentrations and profiles of 19 perfluoroalkyl substances (PFASs) in the muscle and liver of four freshwater species from Lake Trasimeno (Italy): (European eel), (goldfish), (European perch), and (red swamp crayfish). In livers, the amount of PFASs ranged from 3.1 to 10 µg kg, significantly higher than that in muscle (0.
View Article and Find Full Text PDFThe term noninvasive tumor with a follicular growth pattern and nuclear features of papillary thyroid cancer (NIFTP) is used to describe a tumor currently considered as a pre-malignant lesion for which a conservative therapeutic approach (i.e., lobectomy without radioiodine therapy) is strongly suggested.
View Article and Find Full Text PDFArticle Synopsis
- Ostreopsis cf. ovata, a marine microalgae, produces toxic compounds called ovatoxins (OVTXs) that pose risks to animal and human health.
- In experiments, gilthead seabreams fed with mussels contaminated by OVTXs exhibited changes in lipid metabolism and began rejecting food after six days, even though OVTX levels were undetectable in their tissues.
- The findings suggest that while OVTXs might not accumulate in fish from contaminated diets, they still cause significant physiological effects, raising concerns about human consumption of affected seafood.