Publications by authors named "M C Sanchez-Pozo"
Article Synopsis
- Biomedical science is improving in transparency and reproducibility, which is crucial for research involving semen analysis.
- Two key documents have been released: the WHO Laboratory Manual and the International Standard ISO 23162:2021, both focusing on semen examination protocols.
- It is recommended that authors adhere to these guidelines when publishing their studies, ideally using a provided checklist for proper compliance.
Background: Early identification of patients with COVID-19 who may develop critical illness is of great importance.
Methods: In this study a retrospective cohort of 264 COVID-19 cases admitted at Macarena University was used for development and internal validation of a risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19. Backward stepwise logistic regression was used to derive the model, including clinical and laboratory variables predictive of critical illness.
Study Question: Are studies on semen quality in men exposed to persistent pesticides reported according to the 'strengthening the reporting of observational studies in epidemiology' (STROBE) recommendations and the guidelines for the appraisal of semen quality studies (SEMQUA)?
Summary Answer: Most studies of the impact of pesticides on semen quality do not follow the STROBE and SEMQUA guidelines, thus adherence is low, especially in methodological aspects.
What Is Known Already: Much of the controversy about reduced semen quality in recent decades arises from a lack of standardization in the methodology applied, despite the existence of several validated instruments for evaluating the quality of reporting. Indeed, SEMQUA was purpose-designed for the particular characteristics of semen quality studies.
Study Question: Is there a need for a specific guide addressing studies of seminal quality?
Summary Answer: The proposed guidelines for the appraisal of SEMinal QUAlity studies (SEMQUA) reflect the need for improvement in methodology and research on semen quality.
What Is Known Already: From an examination of other instruments used to assess the quality of diagnostic studies, there was no guideline on studies of seminal quality.
Study Design, Size And Duration: Through systematic bibliographic search, potential items were identified and grouped into four blocks: participants, analytical methods, statistical methods and results.