Unsafe Care and Fake News in Freeman-Burian Syndrome.

Freeman-Burian syndrome is a rare craniofacial syndrome surrounded by fake news. This situation shows the strong connection between the quality of a literature search and clinical reasoning displayed in patient care, especially in care of patients with rare conditions.

Atg8/LC3 controls systemic nutrient surplus signaling in flies and humans.

Organisms experience constant nutritional flux. Mechanisms at the interface of opposing nutritional states-scarcity and surplus-enable organismal energy homeostasis. Contingent on nutritional stores, adipocytes secrete adipokines, such as the fat hormone leptin, to signal nutrient status to the central brain.

Transplantation, Waitlist Status, and County Indices of Economic Health in West Virginia.

Key Points: Patients with ESKD coming from impoverished counties are less likely to be waitlisted or transplanted. Insurance status modified the relationship between county poverty rates and waitlisting/transplant.

Background: Kidney transplantation is the optimal treatment for patients with ESKD.