Hypercoagulability status, operative mortality, and long-term survival in patients operated on for mesenteric venous thrombosis.

Objective: Mesenteric venous thrombosis (MVT) is a rare cause of acute surgical abdomen, with high mortality. The aim of this study was to analyze long-term outcomes and possible factors influencing its prognosis.

Methods: All patients who underwent urgent surgery for MVT from 1990 to 2020 in our center were reviewed.

Comparative study of postoperative complications after open and laparoscopic surgery of the perforated peptic ulcer: Advantages of the laparoscopic approach.

Background: Despite the acceptance of the laparoscopic approach for the treatment of perforated peptic ulcers, its definitive implantation is still a matter of discussion. We performed a comparative study between the open and laparoscopic approach focused on postoperative surgical complications.

Methods: Retrospective observational study in which patients operated on for perforated peptic ulcus in our center between 2001 and 2017 were analyzed.

Semen quality in non-Hodgkin lymphoma survivors: a monocentric retrospective study.

Study Question: How is semen quality affected by treatment in survivors of non-Hodgkin lymphoma (NHL)?

Summary Answer: Before cancer treatment, most NHL subjects were normozoospermic and, while standard first-line treatments seemed compatible with post-treatment recovery after 18 months, salvage therapy followed by haematopoietic stem cell transplant caused permanent damage to spermatogenesis in many cases, with 66% azoospermic subjects in the long term.

What Is Known Already: Testicular function has been widely investigated in relation to the most common malignancies in men of reproductive age, such as testicular cancer and Hodgkin lymphoma, but NHL has been somewhat under-investigated. The available reports generally show a post-treatment worsening of semen parameters in NHL survivors, but they involved small caseloads or a subgroup of broader caseloads, and their results are not comparable.

elicits TLR3 expression but disrupts the inflammatory signaling down-modulating NFκB and IRF3 transcription factors in human Sertoli cells.

, the leading cause of bacterial sexually transmitted diseases worldwide, can disseminate and localize to the upper genital tract impairing reproductive function. Specifically, ascending genital infection has been demonstrated to cause epididymitis or epididymo-orchitis, well-known risk factors for male infertility. possesses the ability to infect primary human Sertoli cells, key elements for the spermatogenetic process and the immune protection of germ cells.