The aim of our study was to determine whether a relationship existed between echocardiographic evidence of left ventricular thrombus (LVT) and clinical course of myocardial infarction. We followed 143 patients who had had typical myocardial transmural infarction (82 with "anterior") and 61 with "inferior" myocardial infarction) over a three month period. Incidence of LVT, detected by Two-Dimensional Echocardiography (TDE) was significantly greater in subjects affected by "anterior" myocardial infarction (p less than 0.
View Article and Find Full Text PDFWe have investigated the presence of serum factors (serum inhibitory factor and rosette inhibitory factor) which inhibit the blastogenic response to phytohemagglutinin and E-rosette function of normal lymphocytes in patients affected with dilated cardiomyopathy. We found them to be present in significantly higher levels with respect to a "control disease" group (P less than 0.05) and normal subjects (P less than 0.
View Article and Find Full Text PDFWe have compared the effects of intravenous administration of cimetidine and ranetidine on some cardiovascular parameters. Five healthy volunteers received both cimetidine (3, 5 mg/Kg) and ranetidine (1, 5 mg/Kg). Heart rate, blood pressure and PEP/LVET were recorded at baseline and 5, 10, 30, 45 minutes after administration of both drugs.
View Article and Find Full Text PDFBoll Soc Ital Biol Sper
July 1982
In this paper we evaluated whether a block of cardiac H2 histamine receptors by ranetidine could modify some non-invasive indices of cardiac function: PEP/LVET, heart rate, blood pressure. Five healthy volunteers underwent studies in baseline conditions and 5, 10, 15, 30, 45 minutes following i.v.
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