Publications by authors named "M C Nigro"
Alzheimer's disease (AD) is a neurodegenerative pathology covering about 70% of all cases of dementia. It is associated with neuroinflammation and neuronal cell death, which are involved in disease progression. There is a lack of effective therapies, and halting this process represents a therapeutic challenge.
View Article and Find Full Text PDFBackground: Long COVID is a heterogeneous clinical syndrome characterised by a variety of reported symptoms and signs. Its clinical management is expected to differ significantly worldwide.
Methods: A survey-based study investigating long COVID-related standard operating procedures (SOPs) has been conducted by the European Respiratory Society (ERS) END-COVID clinical research collaboration with the support of other international societies (ALAT, APSR, CHEST, ESCMID and PATS).
Thiophene-based nanoparticles (TNPs) are promising therapeutic and imaging agents. Here, using an innovative phage-templated synthesis, a strategy able to bypass the current limitations of TNPs in nanomedicine applications is proposed. The phage capsid is decorated with oligothiophene derivatives, transforming the virus in a 1D-thiophene nanoparticle (1D-TNP).
View Article and Find Full Text PDFArticle Synopsis
- Bronchiectasis is a chronic lung condition marked by the permanent widening of airways, leading to symptoms like cough and sputum production, with rising global incidence possibly linked to better imaging and awareness.
- Recent studies show a significant increase in mortality rates among bronchiectasis patients, ranging from 16-24.8% over 4-5 years, though prevalence data can vary widely, indicating possible underreporting and methodological issues in research.
- This review aims to summarize current epidemiological data on bronchiectasis, including its incidence, prevalence, mortality, healthcare costs, and factors affecting its distribution across different geographic areas.