Publications by authors named "M C Negritto"

is a halophytic pantropical invasive fern growing in mangroves and swamps. Its association with arbuscular mycorrhizal fungi (AMF) has been reported in Asia. AMF and their symbiosis (AM) commonly colonise the absorption organs of terrestrial plants worldwide.

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RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, in mutant budding yeast cells can suppress both their ionizing radiation (IR) sensitivity and homologous recombination repair (HRR) defects. Intriguingly, we observed that supports DSB repair by a mechanism of HRR that conserves genome structure and is independent of the canonical HR machinery.

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Living organisms encounter various perturbations, and response mechanisms to such perturbations are vital for species survival. Defective stress responses are implicated in many human diseases including cancer and neurodegenerative disorders. Phenol derivatives, naturally occurring and synthetic, display beneficial as well as detrimental effects.

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The Andean Puna is an arid, high-elevation plateau in which plants such as grasses experience high abiotic stress and distinctive environmental conditions. We assessed colonization by arbuscular mycorrhizal fungi (AMF) and dark septate endophytes (DSE) in the roots of 20 native grass species and examined the relationship between root-associated fungi (AMF and DSE) as a function of the elevation of study sites, the photosynthetic pathways of the grass hosts, and the hosts' life cycles. In general, grasses were co-colonized by AMF and DSE and the colonization by AMF and DSE was not extensive.

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Phenolic compounds and their derivatives are ubiquitous constituents of numerous synthetic and natural chemicals that exist in the environment. Their toxicity is mostly attributed to their hydrophobicity and/or the formation of free radicals. In a continuation of the study of phenolic toxicity in a systematic manner, we have examined the biological responses of to a series of mostly monosubstituted phenols utilizing a quantitative structure-activity relationship (QSAR) approach.

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