Publications by authors named "M C Morrone"
Article Synopsis
- The study aimed to explore gender differences in the phenotypical expression of Behçet's disease (BD) using data from the International AIDA Network Registry, focusing on damage index, disease manifestations, and cardiovascular risk.
- A total of 1024 patients (567 males and 457 females) were examined, revealing that males had a significantly higher overall damage index and more frequent occurrences of uveitis and vascular involvement, while females showed higher instances of arthralgia, arthritis, and CNS involvement.
- Key factors associated with major organ involvement included male gender, treatment with biologic agents, origin from endemic regions, and longer disease duration, indicating a more severe course of BD in males compared to females.
Background: Established equations to predict peak oxygen uptake (VOmax) in healthy subjects are not directly applicable to patient populations, including people with multiple sclerosis (PwMS). PwMS, who commonly exhibit impaired cardiorespiratory and neuromuscular function, often require tailored predictive models. This study aimed at (1) testing the validity, reliability, and accuracy of four widely used formulae, developed in healthy populations, to estimate VOmax in mildly to moderately disabled women with MS, and (2) develop adjusted formulae tailored on MS features.
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- Most research on visual system development has concentrated on early stages up to the primary visual cortex (V1), leaving higher visual areas less understood.
- The typical assumption is that these higher areas mature in a set sequence based on their adult positions, but new evidence suggests this process involves unique network configurations rather than simply being smaller versions of the adult hierarchy.
- Future studies should adopt a network-level approach to better understand normal development, pinpoint risks for developmental disorders, and create effective treatments.
Article Synopsis
- The study focused on understanding neuropathic pain in different types of spondyloarthritis (SpA), such as axial SpA, psoriatic arthritis, and undifferentiated peripheral SpA, aiming to identify its prevalence, characteristics, and risk factors.
- Conducted at two rheumatology centers, the research involved 177 patients and utilized specific questionnaires to assess neuropathic pain, revealing that 22.2% likely experienced significant neuropathic pain while 64.9% showed no significant issues.
- Findings indicated that factors like gender and obesity influenced pain scores, and notable correlations were found between neuropathic pain and clinical disease activity, stressing the need for routine pain assessments in SpA treatment.
Recognizing and understanding the actions of others through motion information are vital functions for social adaptation. Conditions like neurological disorders and motor impairments can impact sensitivity to biological motion, highlighting the intricate relationship between perceiving and executing movements. Our study centred on assessing the ability of children, encompassing both those with typical development and those diagnosed with cerebral palsy due to periventricular leukomalacia (PVL), to discriminate between depicted grasping of a small cylinder and a large cube.
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