Publications by authors named "M C Milfort"

Article Synopsis
  • Heat stress (HS) negatively affects water balance in broiler chickens by disrupting kidney function, specifically the aquaporins (AQPs) that help regulate water permeability.
  • The study evaluated the expression of kidney AQPs and blood composition in broilers under different conditions, including thermoneutral settings and cyclic heat stress, with and without glucose supplementation.
  • Results showed higher expressions of AQPs in heat-stressed birds, increased water consumption, and elevated blood glucose levels, indicating that AQPs play a crucial role in water management during heat stress in chickens.
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Article Synopsis
  • Birds exhibit molecular differences in water intake, categorized as high residual water intake (HRWI) and low residual water intake (LRWI), based on their actual water consumption versus what is expected given their metabolic rates.
  • In LRWI birds, there is a notable increase in kidney metabolites like glucose and fructose, while specific sodium-glucose cotransporters (SGLTs) show altered expression levels that suggest a role in water regulation.
  • The increased expression of the SGLT4 transporter and GLUT2 in LRWI birds is hypothesized to enhance water efficiency and glucose retention, influencing their overall drinking behavior.
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Methionine (Met) supplementation is common practice in broilers to support nutrition, yet there are gaps in the understanding of its role in systemic physiology. Furthermore, several different Met sources are available that may have different physiological effects. This study evaluated the mode of action of Met deficiency (no Met-supplementation) and supplementation (0.

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Eimeria (E.) maxima parasite infects chickens' midgut disrupting the jejunal and ileal mucosa causing high morbidity and mortality. Heat stress (HS) is a seasonal stressor that impacts biological functions leading to poor performance.

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Reduced feed intake during heat stress (HS) disrupts glucose homeostasis, thereby resulting in endoplasmic reticulum (ER) stress and triggering apoptosis in chickens. We hypothesize that glucose supplementation could reduce apoptosis in chickens raised under HS. This study comprised 456 28-day-old broiler chickens randomly assigned to four treatment combinations under glucose supplementation and HS.

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