Publications by authors named "M C Meriggiola"

Background: Genitourinary syndrome of menopause (GSM) is a condition affecting many postmenopausal women. Among the available treatments, the vaginal natural oxygenation device (VNOD) is a new promising option.

Aim: To evaluate the safety and the effectiveness of vaginal high concentration (HC) oxygen (O) and hyaluronic acid (HA) in postmenopausal women with vaginal atrophy (VA).

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Article Synopsis
  • The study focuses on the effects of gender-affirming hormone therapy (GAHT) on bone health in transgender and gender-diverse individuals assigned female at birth (AFAB), specifically comparing those who have undergone bilateral oophorectomy (BO) and those who have not.
  • Over 240 TGD AFAB participants were assessed for bone density using dual-energy X-ray absorptiometry scans at the start and after 5-10 years on GAHT, revealing a decline in bone density after 5 years, particularly in individuals who had undergone BO.
  • Findings indicate that physically active individuals maintained better bone density, while GAHT led to significantly lower estradiol levels after 5 years, which correlated with
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Transgender and gender-diverse (TGD) individuals continue to experience harassment and discrimination across various aspects of life, significantly impacting their physical and mental health. The scarcity of data on their general health, particularly regarding dietary habits, remains a challenge in developing effective healthcare strategies for this population. To address this gap, we analyzed selected dietary habits, physical activity (PA), and body mass index (BMI) among Italian TGD adults compared to the Italian general population (IGP).

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Introduction: Male contraception with exogenously administered hormones suppresses both luteinizing hormone and follicle stimulating hormone leading to low intratesticular testosterone concentration. This results in reversible suppression of spermatogenesis and marked decrease in sperm output in the ejaculate and preventing pregnancy in the female partner.

Prior Studies: Studies of testosterone administered alone or in combination of another gonadotropin suppressive agent such as a progestin or gonadotropin releasing hormone (GnRH) analog showed decisively that the exogenous hormone administrations are effective in suppressing sperm output with few adverse events that are not anticipated.

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