Publications by authors named "M C Manoj"

Background  Type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) frequently coexist due to overlapping risk factors such as metabolic syndrome and obesity. T2DM exacerbates the progression of NAFLD, increasing the risk of cirrhosis and hepatocellular carcinoma. Thus, early detection of liver fibrosis is crucial to prevent severe liver disease.

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: Effective management of acute pancreatitis (AP) hinges on prompt volume resuscitation and is adversely affected by delays in diagnosis. Given diverse clinical settings (tertiary care vs. community hospitals), further investigation is needed to understand the impact of the initial setting to which patients presented on clinical outcomes and quality of care.

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Background: While cochlear implantation (CI) and electric acoustic stimulation (EAS) have a positive outcome in most cases, their effectiveness varies depending on the etiology of the hearing loss. Among the various etiologies, genetic factors are the leading cause of hearing loss and may impact CI and EAS outcomes.

Aims/objectives: To reveal the genetic background of the hearing loss in CI/EAS patients in each ethnic population, we undertook a multi-center study involving the genetic testing of hearing loss in CI/EAS patients from 10 centers.

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Article Synopsis
  • A study was conducted to examine the link between whole blood viscosity (WBV) and sensorineural hearing loss (SNHL) in Indian patients with type 2 diabetes mellitus (T2DM), as diabetes may alter blood viscosity.
  • Among 60 participants, a significant 73.3% had SNHL, primarily moderate and bilateral, with results showing a clear correlation between poorer glycemic control and increased severity of SNHL.
  • However, the study found no significant relationship between WBV and SNHL, microangiopathies (like retinopathy and neuropathy), or glycemic control indicators, suggesting that while SNHL is common in diabetics, blood viscosity might not play a crucial role in its development.
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