Aqueous Extract of Cornus officinalis Alleviate NAFLD via Protecting Hepatocytes Proliferation through Regulation of the Tricarboxylic Acid Cycle.

Ethnopharmacological Relevance: Cornus officinalis (CO) has been widely used as Chinese herbal medicine and has a good clinical efficacy in liver disease. In particular, it has a significant therapeutic effect on metabolic liver disease. However, systematic pharmacological studies on its hepatoprotective effect on non-alcoholic fatty liver disease (NAFLD) are lacking.

Enhancing CO2 Electroreduction to Multicarbon Products by Modulating the Surface Microenvironment of Electrode with Polyethylene Glycol.

Modulating the surface microenvironment of electrodes stands as a pivotal aspect in enhancing the electrocatalytic performance for CO2 electroreduction. Herein, we propose an innovative approach by incorporating a small amount of linear oligomer, polyethylene glycol (PEG), into Cu2O catalysts during the preparation of the CuPEG electrode. The Faradaic efficiency (FE) toward multicarbon products (C2+) increases from 69.

facilitates tumor-derived CCL5 to recruit dendritic cell and suppress colorectal tumorigenesis.

Gut microbes play a crucial role in regulating the tumor microenvironment (TME) of colorectal cancer (CRC). Nevertheless, the deep mechanism between the microbiota-TME interaction has not been well explored. In this study, we for the first time discovered that () effectively suppressed tumor growth both in the AOM/DSS-induced CRC model and the spontaneous adenoma model.

Data Poisoning Attack on Black-Box Neural Machine Translation to Truncate Translation.

Neural machine translation (NMT) systems have achieved outstanding performance and have been widely deployed in the real world. However, the undertranslation problem caused by the distribution of high-translation-entropy words in source sentences still exists, and can be aggravated by poisoning attacks. In this paper, we propose a new backdoor attack on NMT models by poisoning a small fraction of parallel training data.

Natural ingredients in the regulation of abnormal lipid peroxidation: a potential therapy for pulmonary diseases.

Pulmonary diseases are a major category of diseases that pose a threat to human health. The most common drugs currently used to treat lung diseases are still chemical drugs, but this may lead to drug resistance and damage to healthy organs in the body. Therefore, developing new drugs is an urgent task.