How a neurotransmitter drives brainwashing during sleep.

Pulsating blood vessels push fluid into and out of the brains of slumbering mice.

Fish could personalize cancer treatments.

The first clinical trial of zebrafish embryos acting as cancer "avatars" will start soon.

Methods to Manage Edema and Reduce Flap Compression in Postoperative Nursing Care Following Trauma to the Lower Extremity.

Lower extremity edema and compression are potential causes of poor soft tissue healing and flap failure for patients who suffer lower extremity trauma. This review summarizes techniques aimed at reducing edema and mechanical pressure in these patients as well as those undergoing soft tissue coverage techniques. We conducted a literature review for postoperative nursing management to reduce edema in the lower extremity, following traumatic injury.

Sequence specificity of an essential nuclear localization sequence in Mcm3.

Proteins with nuclear localization sequences (NLSs) are directed into the cell nucleus through interactions between the NLS and importin proteins. NLSs are generally short motifs rich in basic amino acids; however, identifying NLSs can be challenging due to the lack of a universally conserved sequence. In this study, we characterized the sequence specificity of an essential and conserved NLS in Mcm3, a subunit of the replicative DNA helicase.