Publications by authors named "M C Hollstein"
Background: Multiparameter immunoblot testing is increasingly used as an alternative to multiple individual IgE analyses for type 1 allergies. This study investigated the performance of an inexpensive immunoblot method, the RIDA qLine allergy test system (R-Biopharm AG), vs. the current gold standard.
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- The study investigates inflammatory skin diseases by analyzing lesional and nonlesional skin using skin microdialysis to get better insights into their proteomic characteristics.
- Samples from patients with atopic dermatitis, psoriasis vulgaris, and prurigo nodularis were analyzed alongside healthy controls to identify differences in cytokine levels and metabolic processes.
- Key findings indicate that lesional skin from psoriasis and prurigo nodularis showed distinct proteomic profiles compared to nonlesional skin, with specific cytokines like IL-8, IL-22, MCP-1, and IL-12p40 potentially serving as biomarkers for these conditions.