Under the surface: Low cardiac vagal tone and poor interoception in young adults with subclinical depressive symptoms.

Introduction: Depressive symptoms are associated with alterations in central and autonomic nervous system activity, including misperception of bodily activity (e.g., low interoception), somatic symptoms and decreased vagally mediated heart rate variability (vmHRV).

TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.

SARS-CoV-2 is a highly transmissible virus that causes COVID-19 disease. Mechanisms of viral pathogenesis include excessive inflammation and viral-induced cell death, resulting in tissue damage. Here we show that the host E3-ubiquitin ligase TRIM7 acts as an inhibitor of apoptosis and SARS-CoV-2 replication via ubiquitination of the viral membrane (M) protein.

A biological rhythm in the hypothalamic system links sleep-wake cycles with feeding-fasting cycles.

The hypothalamus senses the appetite-regulating hormones and also coordinates the metabolic function in alignment with the circadian rhythm. This alignment is essential to maintain the physiological conditions that prevent clinically important comorbidities, such as obesity or type-2 diabetes. However, a complete model of the hypothalamus that relates food intake with circadian rhythms and appetite hormones has not yet been developed.

butterfly flashiness crucially depends on wing scale curvature.

butterflies are widely known for their brilliant blue and flashy colours, which are produced by intricate wing scale structures. Not all species display a vibrant structural coloration; some are whitish or even brown. This suggests that there is considerable interspecific variation in wing scale anatomy, pigmentation and flashiness.