Publications by authors named "M C Galaverni"
Current Radiotherapy Management of Extensive-Stage Small-Cell Lung Cancer in the Immunotherapy Era: An Italian National Survey on Behalf of the Italian Association of Radiotherapy and Clinical Oncology (AIRO).
Curr Oncol
November 2024
Article Synopsis
- A study was conducted to assess current treatment practices for extensive-stage small-cell lung cancer (ES-SCLC) among Italian clinicians, especially regarding the use of radiation therapy.
- The survey involved 225 cancer care professionals, with 90 responding, mainly radiation oncologists with significant experience; the results highlighted a preference for combining chemotherapy with immunotherapy and the common use of prophylactic cranial irradiation (PCI).
- The findings revealed variability in treatment approaches for ES-SCLC, indicating a need for further clinical trials and improved multidisciplinary strategies for managing these patients.
Background: Chemoradiation therapy (CRT) is the treatment of choice for locally advanced non-small cell lung cancer (LA-NSCLC). Several clinical trials that combine programmed cell death 1 (PD1) axis inhibitors with radiotherapy are in development for patients with LA-NSCLC. However, the effect of CRT on tumor cells programmed cell death ligand-1 (PD-L1) expression is unknown.
View Article and Find Full Text PDFAims: SCLC is the most aggressive lung cancer histology with a 5-year OS <10%. At the diagnosis, almost two-thirds of the SCLC an Extended Disease presentation. Two randomized studies (CASPIAN and ImPower133) demonstrated an OS improvement, when immunotherapy was prescribed as maintenance therapy after standard chemotherapy.
View Article and Find Full Text PDFWe estimated the current size and dynamics of the wolf population in Tuscany and investigated the trends and demographic drivers of population changes. Estimates were obtained by two different approaches: (i) mixed-technique field monitoring (from 2014 to 2016) that found the minimum observed pack number and estimated population size, and (ii) an individual-based model (run by Vortex software v. 10.
View Article and Find Full Text PDFThe present study aimed to evaluate the clinical and radiological 1-year outcomes of uterine artery embolization (UAE) performed in a selected population of women with symptomatic myomas and who do not wish to conceive. Between January 2004 and January 2018, a total of 62 patients with pre-menopausal status and with no wish to conceive in the future underwent UAE for the treatment of symptomatic fibroids. All the patients underwent magnetic resonance imaging (MRI) and/or transvaginal ultrasonography (TV-US) before and after the procedure at 1-year follow-up.
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