Publications by authors named "M C Edmondson"

Hourglass fascicular constrictions have been reported in fewer than 100 cases globally and only in the upper limb. The etiology remains unknown. Patients often present with self-limiting pain in the affected limb followed by flaccid paralysis.

View Article and Find Full Text PDF

Graphene is a class of two-dimensional (2D) nanomaterials composed of single or multiple layers of carbon atoms. To date, there are limited clinical data and no epidemiological research available to assess graphene toxicity in humans. Despite the growing amount of animal toxicity data, there are currently no occupational exposure limits (OELs) for any type of graphene nanomaterial published by international authoritative organizations to ensure their safe handling within workplaces.

View Article and Find Full Text PDF

On-surface synthesis of functional molecular structures provides a route to the fabrication of materials tailored to exhibit bespoke catalytic, (opto)electronic, and magnetic properties. The fabrication of graphene nanoribbons via on-surface synthesis, where reactive precursor molecules are combined to form extended polymeric structures, provides quasi-1D graphitic wires that can be doped by tuning the properties/composition of the precursor molecules. Here, we combine the atomic precision of solution-phase synthetic chemistry with on-surface protocols to enable reaction steps that cannot yet be achieved in solution.

View Article and Find Full Text PDF
Article Synopsis
  • Sparse data bias is an issue in data analysis, especially for rare binary outcomes, and while a two-step meta-analysis can help, it doesn't fully eliminate bias in effect estimation.
  • The authors propose a new algorithm called ODAP-B, which utilizes modified Poisson regression to estimate relative risk more accurately and efficiently than traditional methods.
  • Evaluations through simulations and real-world data reveal that ODAP-B provides closer effect estimates and is more privacy-preserving since it only requires aggregated data.
View Article and Find Full Text PDF

Objective: Patients who undergo interhospital transfer, particularly for intensive care unit (ICU) care, experience greater length of stay and mortality. There is evidence that patients transferred for surgical ICU care experience higher mortality rates; however, differences in length of stay or mortality across other ICU types remain unclear. The goals of this work were to assess how length of stay and mortality differ by ICU subspecialties.

View Article and Find Full Text PDF