Publications by authors named "M C Dalman"

Chronic injury- or disease-induced joint impairments result in asymmetric gait deviations that may precipitate changes in joint loading associated with pain and osteoarthritis. Understanding the impact of gait deviations on joint reaction forces (JRFs) is challenging because of concurrent neurological and/or anatomical changes and because measuring JRFs requires medically invasive instrumented implants. Instead, we investigated the impact of joint motion limitations and induced asymmetry on JRFs by simulating data recorded as 8 unimpaired participants walked with bracing to unilaterally and bilaterally restrict ankle, knee, and simultaneous ankle + knee motion.

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The structure of the developing musculoskeletal system during childhood and adolescence influences tissue loading and function. Anatomical features important for musculoskeletal loading such as muscle volume and limb proportion vary with age but limited available anatomical data for the developing limb makes predicting loads challenging. Our aim was to evaluate whether anthropometric scaling of an existing adult musculoskeletal upper limb model is sufficient to accurately represent pediatric strength.

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Background: Methicillin-resistant Staphylococcus aureus (MRSA) is common in medical institutions. We sought to examine the prevalence of S aureus on environmental surfaces in nursing homes and to obtain molecular information on contaminating strains.

Methods: A total of 259 environmental samples were collected from 7 different nursing homes in Northeast Ohio (NEO), from suburban, urban, and rural settings.

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We analyzed microarray expression data to highlight biological pathways that respond to embryonic zebrafish Leptin-a () signaling. Microarray expression measures for 26,046 genes were evaluated from morpholino oligonucleotide "knockdown", recombinant Leptin-a "rescue", and uninjected control zebrafish at 72-hours post fertilization. In addition to KEGG pathway enrichment for phosphatidylinositol signaling and neuroactive ligand-receptor interactions, Gene Ontology (GO) data from rescue zebrafish include JAK/STAT cascade, sensory perception, nervous system processes, and synaptic signaling.

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Article Synopsis
  • - A study was conducted in Iowa with 59 participants to explore the microbiomes of livestock workers, with a focus on their nasal and throat microbiota compared to those without livestock contact.
  • - Findings showed that livestock workers had a more diverse microbiome, with significant differences in nasal samples, especially in types of bacteria like Streptococcus and Proteobacteria.
  • - The study is notable for being the first to detail the microbiomes of livestock workers, revealing that those with exposure to swine might carry more pathogenic organisms in their oropharynx.
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