Publications by authors named "M C Colucci"
Background: The Mobility Scale for Acute Stroke Patients (MSAS) was developed to discriminate between the lower levels of mobility in acute stroke patients in the first two weeks post-onset.
Objective: The present study aims to develop and validate an Italian version of the MSAS.
Methods: The English version of the MSAS was translated into Italian according to international guidelines.
Background: Bioaerosols can represent a danger to health. During SARS-CoV-2 pandemic, portable devices were used in different environments and considered a valuable prevention tool. This study has evaluated the effectiveness of the air treatment device "AEROK 1.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how coagulation factor X (FX) impacts tumor growth in castration-resistant prostate cancer (CRPC) by examining the prostate tumor microenvironment in mouse models through single-cell RNA sequencing.
- It finds that immunosuppressive neutrophils (PMN-MDSCs) produce FX, which activates pathways that enhance tumor cell growth independent of androgens, indicating a role for FX in cancer progression.
- Targeting FXa could impede the oncogenic function of PMN-MDSCs and potentially improve treatment outcomes when combined with existing therapies, with high levels of FX and related markers correlating to worse survival in CRPC patients.
Article Synopsis
- Immune-checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs), with immune-mediated pneumonitis (im-PN) being a rare but serious complication that requires prompt diagnosis and management to prevent severe outcomes and allow for continued cancer treatment.
- A study collected data from 1004 cancer patients treated with ICIs, finding that 24 (2%) developed im-PN, with varying degrees of severity; most patients responded well to steroid treatment, leading to recovery in 21 individuals within an average of 14 weeks.
- Three main radiologic patterns of im-PN were identified (organizational pneumonia-like, pulmonary eosinophilia, and hypersensitivity pneumonitis), and bronchoalve
ARCAPA echocardiographic diagnosis. A network of small multiple coronary vessels, a systo-diastolic jet of flow into the pulmonary artery and a retrograde inverted «blue» flow into the RCA are the key signs. CT-scan confirms the diagnosis .
View Article and Find Full Text PDF