Cuatrec. and (Kunth) Cass.: Chemical and Enantioselective Analyses of Two Unprecedented Essential Oils from Ecuador.

This study presents the first chemical and enantioselective analyses of essential oils (EOs) derived from the leaves of two endemic species, Cuatrec. and (Kunth) Cass., from Loja, Ecuador.

Fetal Isolated Single Umbilical Artery (ISUA) and Its Role as a Marker of Adverse Perinatal Outcomes.

Single umbilical artery (SUA) is considered an ultrasound marker of anomalies. Although it may be present in about 0.5% to 6% of normal pregnancies, it has been linked with an increased risk of fetal growth restriction (FGR), as well as cardiac, genitourinary and gastrointestinal malformations and chromosomal anomalies such as trisomies 21 and 18.

Real-World Data of Patients with V600E-Mutated Metastatic Colorectal Cancer Treated with Trifluridine/Tipiracil.

Background: For patients with refractory metastatic colorectal cancer (mCRC), trifluridine/tipiracil (FTD-TPI) has been associated with a significant improvement in overall survival (OS). However, data are lacking regarding the activity of FTD-TPI in patients with -mutated mCRC.

Methods: This retrospective, multicenter, international cohort included patients with -mutated mCRC treated with FTD-TPI in a real-life setting in Spain and Italy.

Microstructural Assessment of Molybdenum Disulfide Coatings Using Nanoindentation Hardness.

MoS coatings are used extensively in aerospace and defense applications due to their ultralow friction and high wear resistance. Burnished and resin-bonded MoS coatings are commonly used in these applications due to simplicity in deposition and history of use, despite issues with consistency in coating properties and performance. Physical vapor deposition (PVD) of MoS thin films has emerged as a process alternative in the past 50 years, promising far greater control over film structure and composition but at a greater cost.

Utility of Adding Platelet-Rich Plasma to Microneedling vs Microneedling Alone in the Treatment of Acne Scarring.

Acne vulgaris is one of the most common skin diseases worldwide and affects a large population of patients. Post-acne scarring can pose a significant psychosocial burden on patients of all ages; therefore, treatment approaches must be both rapid-acting and effective. Microneedling is a minimally invasive technology that involves the creation of controlled tissue microinjury and subsequent induction of collagen production and tissue remodeling.