Publications by authors named "M C Calhoun"
Article Synopsis
- Researchers assessed circulating tumor DNA (ctDNA) as a biomarker for monitoring cancer treatment in patients with various renal cell carcinoma (RCC) types, finding it could improve clinical outcomes.
- The study involved 92 patients undergoing treatment, monitoring ctDNA changes and their association with progression-free survival (PFS), revealing that patients with serial ctDNA negativity had better PFS compared to those who remained ctDNA positive.
- Results indicate that regular ctDNA monitoring can provide valuable prognostic information during treatment or surveillance, showing strong correlation with patient outcomes.
Background And Objective: Despite curative-intent radical cystectomy (RC), patients with muscle-invasive bladder cancer (MIBC) are at high risk of recurrence. Biomarkers are urgently needed to refine prognostication and selection of appropriate perioperative systemic therapies. Our aim was to evaluate the prognostic and predictive value of tumor-informed circulating tumor DNA (ctDNA) results in a multicenter cohort of patients with bladder cancer who underwent RC.
View Article and Find Full Text PDFProsthetic nasal reconstruction provides a restorative option for patients with nasal defects, and these can be retained with a variety of methods including adhesives and implants. These prostheses can significantly improve appearance, self-esteem, and quality of life for patients and they restore many functions of the external nose. Traditional fabrication methods are often used by the skilled professionals who make these custom prostheses, but digital technology is improving the workflow for design and fabrication of silicone nasal prostheses.
View Article and Find Full Text PDF(1) Background: This study aims to examine pharmacy students' perceptions of their knowledge and competencies in human resource management (HRM) while also investigating their attitudes toward the educational content provided in a didactic HRM course. (2) Methods: A survey evaluating both course knowledge (pre and post) and attitudes was administered to students enrolled in an HRM class. Data were analyzed using descriptive statistics and measures of associations.
View Article and Find Full Text PDFPurpose: Circulating tumor DNA (ctDNA) detection in blood has emerged as a prognostic and predictive biomarker demonstrating improved assessment of treatment response in patients receiving immune checkpoint inhibitors (ICIs). Here, we performed a pilot study to support the role of ctDNA for longitudinal treatment response monitoring in patients with advanced genitourinary (GU) malignancies receiving ICIs.
Materials And Methods: Patients with histologically confirmed advanced GU malignancies were prospectively enrolled.