Publications by authors named "M C Bottineau"
Background: In resource limited settings, children with cardiac disease present late, have poor outcomes and access to paediatric cardiology programmes is limited. Cardiac point of care ultrasound was introduced at several Médecins Sans Frontières sites to facilitate cardiopulmonary assessment. We describe the spectrum of disease, case management and outcomes of cases reviewed over the Telemedicine platform.
View Article and Find Full Text PDFIntroduction: Carney Complex (CNC) is a rare multiple endocrine and nonendocrine neoplasia syndrome. Manifestations and genotype-phenotype correlations have been described by retrospective studies, but no prospective study evaluating the occurrence of the different manifestations has been available so far.
Methods: This multicenter national prospective study included patients with CNC, primary pigmented nodular adrenal disease (PPNAD), or a pathogenic PRKAR1A mutation; after a full initial workup, participants were followed for 3 years with annual standardized evaluation.
Article Synopsis
- Tuberculosis is a widespread illness affecting vulnerable populations, especially in low-resource areas, and is particularly notable for causing lymphadenopathy in children, though this usually isn’t severe.
- A two-year-old malnourished child exhibited an unusual case with painless and significantly enlarged lymph nodes that led to a diagnosis of tuberculosis after fine needle aspiration.
- Successful treatment with anti-tuberculosis therapy emphasizes the need for clinicians to recognize atypical cases for prompt diagnosis and care.
Objective: To rapidly increase childhood immunization through a preventive, multi-antigen, vaccination campaign in Mambéré-Kadéï prefecture, Central African Republic, where a conflict from 2012 to 2015 reduced vaccination coverage.
Methods: The three-round campaign took place between December 2015 and June 2016 using: (i) oral poliomyelitis vaccine (OPV); (ii) combined diphtheria, tetanus and pertussis (DTP) vaccine, type B (Hib) and hepatitis B (DTP-Hib-hepatitis B) vaccine; (iii) pneumococcal conjugate vaccine (PCV); (iv) measles vaccine; and (v) yellow fever vaccine. Administrative data were collected on vaccines administered by age group and vaccination coverage surveys were carried out before and after the campaign.
Objective: To assess the effectiveness of blood transfusions in a hospital of north-eastern Democratic Republic of the Congo.
Methods: Prospective study of children admitted for severe anaemia. During admission, data were collected on clinical condition and haemoglobin levels, before and after blood transfusion.