Publications by authors named "M C Bonomo"
Polyvinyl butyral (PVB) is a high-performance thermoplastic polymer, commonly used as an interlayer material in laminated safety glass for the automotive and architectural sectors. Currently, there is no end-of-life cycle program for a substantial amount of PVB film, which mainly ends up in landfills. According to a circular approach, PVB can be revalorized after efficient separation and recovery from glass.
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- Hepcidin is a hormone linked to iron regulation, produced by colorectal cancer (CRC) cells, and this study investigates its potential as a prognostic biomarker in microsatellite stable (MSS) metastatic CRC (mCRC).
- The research found that mCRC patients with serum hepcidin levels over 40 ng/mL had a significantly lower one-year overall survival rate compared to those with lower levels, indicating a strong link between high hepcidin levels and poorer prognosis.
- Multivariate analysis confirmed that baseline serum hepcidin levels independently predict overall survival in MSS mCRC patients, suggesting it could be a useful marker for assessing treatment outcomes, warranting further research for validation.
In this contribution, we tackle the replacement of the Hg-based catalyst and fossil-derived isocyanate precursors toward the formulation of a more sustainable polyurethane thermosetting resins (PUs), emulating the performance of a fully fossil-based one employed in industrial encapsulation of optoelectronics. A mixed Bi-Zn catalyst and a 71% bio-based isocyanate are exploited at this aim through multivariate chemometric approaches, namely Design of Experiment (DoE). DoE allows us to investigate the effect of different formulation factors on selected parameters, such as the film flexibility and transparency or the gel time.
View Article and Find Full Text PDFBackground And Aims: Scuba diving for people with diabetes was discouraged due to hypoglycemia risks. However, evolving guidelines now enable safe diving for people with diabetes. Among them, the Diabete Sommerso® safety protocol.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) is a heterogeneous disease with an aggressive clinical course and worse outcomes than other breast cancer subtypes. Metastatic triple-negative breast cancer (mTNBC) is characterized by an aggressive clinical course and unfavorable outcomes, despite the pharmacological treatments used. The present clinical case describes a 35-year-old woman affected by TNBC characterized by rapid and subsequent local, cutaneous and lymph node progression of the disease.
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