The extinction burst: Effects of reinforcement magnitude.

The extinction burst is an increase in an operant behavior early in the transition to extinction. A matching-law-based quantitative theory suggests that it results from the elimination of competition from reinforcement-related behavior that accompanies the transition to extinction. This experiment examined the effects of reinforcement magnitude on the extinction burst with rats.

Resurgence mitigation across extended extinction following four and eight cycles of on/off alternative reinforcement.

Resurgence is an increase in an extinguished operant response resulting from a worsening of conditions (e.g., extinction) for a more recently reinforced alternative behavior.

Rescuing T cells from stiff tumors.

In a recent issue of Cell, Zhang et al. demonstrate that mechanical features of a solid tumor can drive T cells into dysfunctionality and identify pathways that revert this "exhausted" state.