Publications by authors named "M Byford"

Background: Handpumps are used by millions of people as their main source of water. Although handpumps represent only a basic form of water provision, there have been continuous efforts to improve the performance of these systems as they are likely to remain in use for many years to come. The introduction of a professional maintenance service in southern Kenya has shown an order of magnitude improvement in operational performance over community-based management, with 90% of handpump faults repaired within 3 days of being reported.

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Objective: Identifying and recruiting people with early pre-symptomatic Alzheimer's disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitment and representativeness of the participants involved. We now report the recruitment and participation patterns from a neuroscience sub-study of the MRC National Survey of Health and Development, "Insight 46".

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Article Synopsis
  • Increasing age is a major risk factor for dementia, with changes related to Alzheimer's disease potentially developing years before symptoms appear.
  • Molecular imaging techniques like PET and MRI help to identify these changes, allowing for earlier detection and intervention before cognitive symptoms manifest.
  • The "Insight 46" study is monitoring 500 individuals from the 1946 British birth cohort to examine the progression of dementia-related changes over time, collecting data through various methods and aiming to identify preclinical stages of Alzheimer's.
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Background: Adolescent mental health problems are associated with a range of adverse outcomes in adulthood but little is known about the effects on adult parenting practices. This study aimed to examine prospective associations between adolescent conduct and emotional problems and subsequent parenting behaviours in adulthood.

Methods: The study sample comprised 1110 members from the MRC National Survey of Health and Development.

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Background: Cognitive ability is an important contributor to life chances, with implications for cycles of advantage or disadvantage across generations. Parenting practices are known to influence offspring cognitive development, but the extent to which these mediate intergenerational continuities and discontinuities in cognitive ability has not been adequately studied.

Methods: We used factor analysis to derive summary measures of parenting practices, and regression analyses and path modelling to test associations between these and cognitive function at age 8 years in 1690 first offspring of the British 1946 birth cohort.

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