Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV.

Background: To understand the effects of frailty, geriatric syndromes, and comorbidity on quality of life and mortality in older adults with HIV (OAWH).

Methods: Cross-sectional study of the FUNCFRAIL multicenter cohort. The setting was outpatient HIV-Clinic.

Different profiles among older adults with HIV according to their chronological age and the year of HIV diagnosis: The FUNCFRAIL cohort study (GeSIDA 9817).

Background: People in their fifties with HIV are considered older adults, but they appear not to be a homogeneous group.

Objective: To evaluate the differences among older adults with HIV according to their chronological age and the year of HIV diagnosis.

Methods: Cross-sectional study of the FUNCFRAIL cohort.

Infections after spine instrumentation: effectiveness of short antibiotic treatment in a large multicentre cohort.

Background And Objectives: Available information about infection after spine instrumentation (IASI) and its management are scarce. We aimed to analyse DAIR (debridement, antibiotics and implant retention) prognosis and evaluate effectiveness of short antibiotic courses on early forms.

Methods: Multicentre retrospective study of patients with IASI managed surgically (January 2010-December 2016).

The Use of Apremilast in Psoriasis: A Delphi Study.

Background: Experience in the use of apremilast in clinical practice complements the information available from pivotal clinical trials.

Material And Method: Following a review of the literature, a panel of dermatologists with expertise in the management of psoriasis considered 5 scenarios in which the evidence supporting the use of apremilast to treat moderate psoriasis is insufficient or controversial. These scenarios were then assessed using a Delphi questionnaire.

Outpatient parenteral antimicrobial therapy for infective endocarditis in patients over 80 years.

Objective: The incidence of infective endocarditis is progressively increasing, especially in elderly patients. Outpatient parenteral antibiotic therapy (OPAT) is being an excellent alternative for treatment, but advanced age is one of the relative contraindications. The aim of this study is to compare the characteristics and prognosis of patients less or more than 80 years, treated with OPAT.