Publications by authors named "M Burghartz"
Background: Suprastomal collapse (SSC) is considered a major late complication of paediatric tracheostomy and can be responsible for decannulation failure in up to 20% of tracheostomised children. Depending on the severity of SSC, surgery may be required. Various strategies and techniques are available, of which the treating with airway team should be aware.
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- Laryngeal chondrosarcoma (LC) is a rare cancer that grows slowly, with laryngeal preservation surgery (LPS) being the main treatment; however, some patients may need multiple surgeries or total laryngectomy (TL).
- The study analyzed data from 21 patients to identify risk factors for recurrence and the need for TL, finding that those with higher-grade tumors (G2) experienced more surgery for recurrences compared to lower-grade tumors (G1).
- Results showed that patients with G2 tumors face significant challenges, including higher recurrence rates and a greater likelihood of requiring TL, while factors like tumor localization and margin status influence outcomes without guaranteeing future surgery needs.
[Impact of benign parotid gland tumors on whole salivary flow rate].
Laryngorhinootologie
August 2020
Objective: The impact of benign tumors of the parotid gland on whole salivary flow or sialochemistry is unclear.
Material And Methods: A total of 22 patients with benign parotid tumors and 18 healthy controls underwent measurements of unstimulated and stimulated whole saliva flow and sialochemistry (Na+, K+, Ca++, Amylase, and pH). Assessment of xerostomia was performed by means of a visual analogue scale (VAS) and a questionnaire (QoL).
In vitro culture of human salivary gland epithelial cells (SGEC) is still a challenge. A high quantity and quality of cells are needed for the cultivation of 3D matrices. Furthermore, it is known that DNA damage is supposed to be an important factor involved in carcinogenesis.
View Article and Find Full Text PDFObjective: The aim of this study was to bring attention to a rather unnoted side effect of salivary gland surgery-reduced salivary flow.
Methods: A systematic PubMed, Cochrane Library, LIVIVO, and Embase databases search was performed to identify relevant articles.
Results: Eight studies matched the inclusion criteria.