Publications by authors named "M Burghammer"
Article Synopsis
- Quantitative X-ray diffraction techniques need careful adjustments for sample transmission, especially in SAXS and WAXS experiments.
- Typical beamstops used in X-ray nanoprobes can’t record transmission signals simultaneously with scattering data, which negatively impacts data quality.
- The paper introduces a novel small beamstop with an embedded metal target to enhance fluorescence detection, allowing for accurate sample transmission measurements using a high-sensitivity avalanche photodiode.
Article Synopsis
- Tau protein is key in various neurological disorders, but the mechanisms of its progression and spread in the brain remain unclear due to difficulties in analyzing tau aggregates.
- Using advanced techniques like micro-x-ray diffraction (µXRD) and micro-X-ray fluorescence (μXRF), researchers studied tau lesions in a 79-year-old male with dementia, revealing distinct forms of tau and their locations in the brain.
- Findings indicated that different types of tau lesions had unique chemical environments, affecting their structure and spread, with higher fibrillar tau density linked to greater sulfur deposition and the presence of metals like zinc and calcium in all tau lesions.
Crystallographic texture is a key organization feature of many technical and biological materials. In these materials, especially hierarchically structured ones, the preferential alignment of the nano constituents heavily influences the macroscopic behavior of the material. To study local crystallographic texture with both high spatial and angular resolution, we developed Texture Tomography (TexTOM).
View Article and Find Full Text PDFOsteosarcoma (OS) is the most common malignant primary bone tumor in humans and occurs in various subtypes. Tumor formation happens through malignant osteoblasts producing immature bone. In the present paper we studied two different subtypes of osteosarcoma, from one individual with conventional OS with massive sclerosis and one individual with parosteal OS, based on a multimodal approach including small angle x-ray scattering (SAXS), wide angle x-ray diffraction (WAXS), backscattered electron imaging (BEI) and Raman spectroscopy.
View Article and Find Full Text PDFUnderstanding the effects of consolidating inorganic mineral treatments on carbonate stones of cultural heritage, and on the nature and distribution of newly formed products within the matrix, poses a significant challenge in Heritage Science and Conservation Science. Existing analytical methods often fail to deliver spatial and compositional insights into the newly formed crystalline phases with the appropriate high lateral resolution. In this study, we explore the capabilities and limitations of synchrotron radiation (SR) micro-X-ray powder diffraction (μXRPD) mapping combined with micro-X-ray fluorescence (μXRF) to give insight into compounds formed following the application of ammonium oxalate (AmOx) and diammonium phosphate-based (DAP) solutions on porous carbonate stone.
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