Publications by authors named "M Buckle"
Article Synopsis
- This paper talks about problems in cancer treatment in Europe, especially how health guidelines and medical recommendations don’t match up.
- It studied different European countries to see if they use advanced cancer tests that doctors recommend.
- The results showed that many countries are not using these advanced tests, which could help patients more, and the paper suggests that health leaders need to pay more attention to these recommendations for better cancer care.
Article Synopsis
- European health systems can improve health by using more technology to prevent diseases and spot them early.
- Right now, they're not using these tools effectively, which means patients aren't getting the best diagnosis or access to new treatments.
- The study looks into how different countries in Europe are handling new health technologies and genetics, and suggests it's a good time to rethink how to use these tools better in healthcare.
To report a case of a macular pucker forming after macular hole (MH) repair with the inverted internal limiting membrane (ILM) flap technique, with resolution after secondary inverted ILM flap peeling. A single case was evaluated. A 76-year-old woman presented with reduced central vision (28 letters) in the right eye.
View Article and Find Full Text PDFStructural fluctuations of nucleosomes modulate the access to internal DNA in eukaryotic cells; clearly characterisation of this fundamental process is crucial to understanding gene regulation. Here we apply PhAST (Photochemical Analysis of Structural Transitions) to monitor at a base pair level, structural alterations induced all along the DNA upon histone binding or release. By offering the first reliable, detailed comparison of nucleosome assembly and disassembly in vitro, we reveal similarities and differences between the two processes.
View Article and Find Full Text PDFGold nanorods (GNRs) can be functionalized with multiple biomolecules allowing efficient cell targeting and delivery into specific cells. However, various issues have to be addressed prior to any clinical applications. They involve controlled biofunctionalization to be able to deliver a known dose of drug by immobilizing a known number of active molecules to GNRs while protecting their surface from degradation.
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