Publications by authors named "M Bucau"
Article Synopsis
- * A study involving 30 Togolese female sex workers analyzed 156 HPV genome sequences from cervical and anal swabs, revealing identical infections but varying genetic diversity across HPV types and sites.
- * Low-risk HPVs showed more mutations induced by APOBEC3 in the E4 and E6 genes compared to high-risk HPVs, which had fewer mutations, suggesting different cancer risk potentials among HPV types.
Article Synopsis
- Ovarian neuroendocrine tumors (NETs) are rare tumors often found in mature teratomas, but there hasn’t been a recent study looking at their characteristics using new tumor markers.
- This study analyzed 34 unilateral NETs, identifying four distinct immunophenotypic profiles and determining the tumors' grade and proliferation rates with specific markers.
- The findings indicate that the most common NET type shows an intestinal phenotype, suggesting a neuroendocrine precursor in the teratoma and emphasizing that these tumors shouldn't be classified based on the surrounding teratoma components.
Introduction: Antiphospholipid syndrome (APS) is a cause of pregnancy morbidity. We aim to determine the frequency of criteria and non-criteria anti-phospholipid (aPL) autoantibodies in patients admitted for unexplained fetal death (UFD), pre-eclampsia (PE) and/or fetal growth restriction (FGR).
Methods: All consecutive patients with UFD, PE and/or FGR followed in the department of Obstetrics, Bichat Hospital, University of Paris, Paris, between January 2019 and December 2021 were screened.
Study Question: What are the pregnancy and obstetric outcomes in women with atypical hyperplasia (AH) or early-stage endometrial cancer (EC) managed conservatively for fertility preservation?
Summary Answer: The study found a live birth rate of 62% in patients with AH or EC after conservative treatment, with higher level of labour induction, caesarean section, and post-partum haemorrhage.
What Is Known Already: Fertility-sparing treatment is a viable option for women with AH or EC during childbearing years, but the outcomes of such treatments, especially regarding pregnancy and obstetrics, need further exploration.
Study Design, Size, Duration: This retrospective cohort study analysed data from January 2010 to October 2022, involving 269 patients from the French national register of patients with fertility-sparing management of AH/EC.
In France, about 2000 new cases of anal cancer are diagnosed annually. Squamous cell carcinoma is the most common histological type, mostly occurring secondary to persistent HPV16 infection. Invasive cancer is preceded by precancerous lesions.
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