Publications by authors named "M Brucoli"
Clinical characteristics, management, and malignancy rate of oral lichen planus: A European multicenter study.
J Stomatol Oral Maxillofac Surg
January 2025
Introduction: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous condition that includes a spectrum of oral clinical manifestations ranging from mild painless white lesions to painful erosions and ulcers. The purpose of this European multicenter study is to describe the general characteristics of OLP lesions, the clinical and histopathological diagnosis, and the management of OLP at different European Oral Medicine and Maxillofacial Surgery centers, in order to minimize selections biases and provide information about the current trends in the treatment of OLP across Europe.
Materials And Methods: Data and histopathological records of patients with OLP were retrospectively revised and only those patients that fulfilled the diagnostic criteria from the 2016 position paper by American Academy of Oral and Maxillofacial Pathology were included.
Background: The treatment of multiple mandibular fractures may often be challenging. The aim of this study was to evaluate the characteristics and outcomes of multiple mandibular fractures, with a focus on triple mandibular fractures.
Material And Methods: Patients with multiple (triple) mandibular fractures were included.
A Multi-Center Observation Study on Medication-Related Osteonecrosis of the Jaw (MRONJ) in Patients with Osteoporosis, and Other Non-Malignant Bone Diseases, in Northwestern Italy over 16 Years.
Biomedicines
September 2024
Article Synopsis
- The study aimed to assess the rise in new cases of Medication-Related Osteonecrosis of the Jaw (MRONJ) among patients with osteoporosis and other non-cancerous bone diseases in Northwestern Italy from 2007 to 2022.
- Researchers analyzed 198 MRONJ cases, finding that the majority were linked to osteoporosis and primarily involved treatments with bisphosphonates.
- The findings revealed a significant increase in new MRONJ cases over the years, with a call for better collaboration among healthcare specialists for early detection and improved patient outcomes.
Epidemiology, etiopathogenesis, and management of MRONJ: A European multicenter study.
J Stomatol Oral Maxillofac Surg
September 2024
Article Synopsis
- The study aimed to analyze the characteristics and risk factors of medication-related osteonecrosis of the jaw (MRONJ) across various European Oral and Maxillofacial Surgery centers, to enhance understanding of its epidemiology and treatment trends.
- Data was collected from 537 patients, revealing significant links between metastatic bone disease, advanced MRONJ stages, male gender, and higher recurrence rates of MRONJ.
- Findings suggest that patients with osteoporosis experienced a longer duration of antiresorptive medication before MRONJ onset, while those with metastatic bone cancer, especially prostate cancer or multiple myeloma, had a shorter duration, emphasizing the importance of surgical intervention in managing MRONJ.
Oral and oropharyngeal malignant minor salivary gland tumors: A retrospective study.
J Stomatol Oral Maxillofac Surg
September 2024
Introduction: Tumors of minor salivary gland origin are uncommon lesions, representing 2-3 % of all malignant neoplasms of the upper aerodigestive tract and 9-23 % of all salivary gland tumors. The aim of this study is to report the demographic features, sites, histological types and the management and outcomes of oral and oropharyngeal minor salivary gland tumors diagnosed and treated in a University Hospital with a multidisciplinary head and neck team.
Materials And Methods: A single-center retrospective observational study was conducted in a cohort of patients who received diagnosis of minor salivary gland carcinoma of oropharynx and oral cavity between July 30th 2000 and 30th September 2021.