Publications by authors named "M Bruckner"
Biomass was the principal energy source in preindustrial societies; their agriculture provided more energy than it required. Thus, the energy return on energy investment (EROEI) needed to be >1. Recent studies have indicated that this may not be the case for modern industrialized agrifood systems (AFSs).
View Article and Find Full Text PDFBackground: Surfactant replacement is standard for preterm neonates with respiratory distress syndrome, improving survival and outcomes. Less invasive surfactant administration (LISA) and intubation-surfactant-extubation (INSURE) are preferred methods for surfactant replacement in spontaneously breathing preterm neonates. Despite the undeniable benefits of surfactant implementation in neonatal care, surfactant administration can affect vital parameters and cerebral oxygenation and perfusion, assessed by near-infrared spectroscopy (NIRS).
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- The Wnt/β-catenin signaling pathway activation relies on the formation of biomolecular condensates through the polymerization of dishevelled 2 (DVL2).
- Researchers used biochemical techniques to identify oligomeric DVL2 complexes in human cell lines, uncovering a crucial low-complexity region (LCR4) that influences complex formation.
- The study reveals that DVL2's activation of the Wnt pathway is dependent on the interaction of specific regions within the protein, highlighting a two-step process for condensate formation involving both high-affinity and low-affinity interaction sites.
Background: Artificial daylight photodynamic therapy (ADL-PDT) is an alternative, all-year applicable, nearly painless treatment approach for actinic keratoses (AK) with comparable effectiveness to daylight or conventional PDT. At the time this study was initiated, methyl aminolevulinate (MAL) was the only photosensitizer approved for ADL-PDT in Germany.
Objective: To gain comprehensive insights into the practicability of MAL-ADL-PDT in patients with AK using different artificial daylight sources under real-world conditions.
Identifying immune correlates of risk following COVID-19 vaccine boosters has become paramount as a result of the challenges in generating additional efficacy data. The trial data described here was collected in the United States, with a large part of the study conduct coinciding with the emergence of the SARS-CoV-2 Omicron BA.1 variant.
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