Publications by authors named "M Brichova"

Aim:  The aim of the article is to summarize observations on cytomegalovirus (CMV) anterior uveitis, and in short case reports present cases of patients treated at our Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague.

Material And Methods:  Retrospective analysis of patients at the Centre for diagnosis and treatment of uveitis from 2003 to 2024. Presentation of our experiences with CMV anterior uveitis confirmed by polymerase chain reaction (PCR) in aqueous humor in case reports.

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The aim of this study was to describe the clinical and molecular genetic findings in seven individuals from three unrelated families with Blau syndrome. A complex ophthalmic and general health examination including diagnostic imaging was performed. The mutational hot spot located in exon 4 was Sanger sequenced in all three probands.

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Purpose: To draw attention to the higher proportion of Fuchs heterochromic iridocyclitis (FHI) cases in patients with multiple sclerosis (MS).

Materials And Methods: Retrospective study of data collected at the Center for the Diagnosis and Treatment of Uveitis.

Results: An analysis of the medical records of 3016 patients with uveitis (in the years 2003-2020) was performed with a focus on MS.

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Aim Of The Study: Comparative cross-sectional study of retinal parameters in Huntington's disease and their evaluation as marker of disease progression.

Clinical Rationale For The Study: Huntington's disease (HD) is a neurodegenerative disorder with dominant motor and neuropsychiatric symptoms. Involvement of sensory functions in HD has been investigated, however studies of retinal pathology are incongruent.

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Article Synopsis
  • The study analyzes the characteristics and treatments of ocular syphilis over the past two decades, focusing on its association with syphilitic uveitis and HIV coinfection.
  • It is based on a retrospective review of 16 patients with confirmed ocular syphilis from a hospital in Prague, revealing a rise in syphilitic uveitis cases and detailing various forms of uveitis observed.
  • The findings suggest that posterior uveitis and optic disc edema are key indicators of ocular syphilis, and that using corticosteroids alongside antibiotics may be beneficial for treating severe cases.
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