Publications by authors named "M Bretthauer"
Importance: Patients of physicians with higher adenoma detection rates (ADRs) during colonoscopy have lower colorectal cancer (CRC) risk after screening colonoscopy (ie, postcolonoscopy CRC). Among physicians with an ADR above the recommended threshold, it is unknown whether improving ADR is associated with a lower incidence of CRC in their patients.
Objective: To determine the association of improved ADR in physicians with a range of ADR values at baseline with CRC incidence among their patients.
Article Synopsis
- AI has the potential to improve gastrointestinal endoscopy, but standardized methods are needed for its effective adoption in clinical practice.
- The QUAIDE Explanation and Checklist was created by a panel of 32 experts to provide guidelines for designing and reporting AI studies in this field.
- Consensus was achieved on 18 recommendations across key areas including data collection, outcome reporting, experimental setup, and result presentation, aiming to enhance research consistency and facilitate the use of AI in clinical settings.
Prediction of metachronous advanced colorectal neoplasia by KRAS mutation in polyps.
United European Gastroenterol J
November 2024
Background: The potential of molecular markers in the removed polys as reliable predictors of metachronous lesions is still uncertain.
Aim: Our aim was to evaluate the role of somatic mutations in KRAS in polyps of patients with high-risk adenomas to predict the risk of advanced polyps or colorectal cancer (CRC) within 3 years.
Methods: A total of 518 patients were prospectively enrolled.
Article Synopsis
- A cross-sectional study in Norway examined adverse events related to colonoscopy in a randomized colorectal cancer screening trial, involving over 10,000 participants.
- Out of those, 2.4% experienced adverse events, ranging from mild to severe, with the most common issues being gastrointestinal bleeding and abdominal pain.
- Key risk factors for adverse events included older age, female sex, and specific medical treatments, highlighting the importance of awareness for endoscopists to reduce risks.