Publications by authors named "M Breguet"
Article Synopsis
- An amendment to the original paper has been released.
- The amendment can be accessed through a provided link.
- This link is located at the top of the paper for easy access.
Article Synopsis
- Hydatidiform mole (HM) is a type of unusual pregnancy where there is abnormal growth of cells and problems with the baby developing.
- There are two main types of HM: complete and partial, and some patients have more than one kind happening in their pregnancies.
- The study found that women with HM have a higher chance of having miscarriages that are caused by chromosomal problems, especially if they are older or have certain types of HM, compared to women without HM.
Androgenetic complete hydatidiform moles are human pregnancies with no embryos and affect 1 in every 1,400 pregnancies. They have mostly androgenetic monospermic genomes with all the chromosomes originating from a haploid sperm and no maternal chromosomes. Androgenetic complete hydatidiform moles were described in 1977, but how they occur has remained an open question.
View Article and Find Full Text PDFHydatidiform mole is an aberrant human pregnancy characterized by early embryonic arrest and excessive trophoblastic proliferation. Recurrent hydatidiform moles are defined by the occurrence of at least two hydatidiform moles in the same patient. Fifty to eighty percent of patients with recurrent hydatidiform moles have biallelic pathogenic variants in NLRP7 or KHDC3L.
View Article and Find Full Text PDFObjective: In rare entities such as gestational trophoblastic disease (GTD), only multi-institutional registries can gather significant number of patients to build up valuable clinical databases. No Canada-wide GTD registry currently exists. We conducted a survey among members of the Canadian Society of Gynecologic Oncology (GOC) to investigate their interest in a pan-Canadian GTD registry.
View Article and Find Full Text PDF