Assessing Lifestyle in a Large Cohort of Undergraduate Students: Significance of Stress, Exercise and Nutrition.

Background/objectives: Lifestyle (in particular, nutrition and exercise) determines present and future youths' health. The goal of the present study was to identify specific student groups who deserve precise lifestyle improvement interventions, tailored to their characteristics.

Methods: An anonymous web-based questionnaire to assess lifestyle was posted on the websites of two main Italian Academic Institutions, and 9423 students voluntarily participated.

Decoding KRAS mutation in non-small cell lung cancer patients receiving immunotherapy: A retrospective institutional comparison and literature review.

Introduction: KRAS mutation the most common molecular alteration in advanced non-small cell lung cancer (NSCLC) and is associated with an unfavourable prognosis, largely due to the lack of targeted therapeutic options for the majority of the KRAS mutated isoforms. The landscape of NSCLC treatment has expanded with the introduction of immune checkpoint inhibitors (ICIs). Nonetheless, data regarding the efficacy of ICI in NSCLC patients harbouring KRAS mutations are conflicting.

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets.

A subset of circulating human platelets stores Tissue Factor (TF) intracellularly, the key activator of the blood coagulation cascade and thrombus formation. Upon platelet activation, TF is exposed on the cell membrane, where it binds to FVII, ultimately leading to thrombin generation. Considering that (1) levels of TF-positive platelets increase in various clinical settings, contributing to the patient's prothrombotic phenotype, and (2) different drugs can modulate platelet-associated TF expression, a standardized method for assessing TF-positive platelets is valuable, as its evaluation has been controversial in the past.

Establishment of recurrent exposures reference levels for repeated computed tomography examinations in adult patients on a nationwide level in Slovakia.

Introduction: The study aims were: (1) to assess the incidence in 1 year, the cumulative incidences and the period prevalence in 3/5 years of the condition of patients accruing cumulative effective dose (CED) ≥ 100 mSv in health care centres providing CT examinations in Slovakia; and (2) to quantify their variability among different centres, to test the feasibility of establishing recurrent exposure reference levels (RERL) on a nationwide level.

Materials And Methods: The data were tracked during five consecutive years using the CT dose index and dose-length-product along with the patient's ID. ED was calculated using conversion factors.