Publications by authors named "M Brachmann"
Lumpfish, , have historically been harvested throughout Atlantic Canada and are increasingly in demand as a solution to controlling sea lice in Atlantic salmon farms-a process which involves both the domestication and the transfer of lumpfish between geographic regions. At present, little is known regarding population structure and diversity of wild lumpfish in Atlantic Canada, limiting attempts to assess the potential impacts of escaped lumpfish individuals from salmon pens on currently at-risk wild populations. Here, we characterize the spatial population structure and genomic-environmental associations of wild populations of lumpfish throughout the Northwest Atlantic using both 70K SNP array data and whole-genome re-sequencing data (WGS).
View Article and Find Full Text PDFProblem: Regarding transmissible viral diseases such as those caused by SARS-CoV-2 virus, one of the key challenges is isolation management until final diagnosis. This study investigates the influence of SARS-CoV-2 point-of-care (POC) PCR on workflow and efficiency in an emergency department (ED) of a tertiary university hospital.
Method: An analysis of 17,875 ED patients receiving either SARS-CoV-2 POC PCR (rapid PCR, 11,686 patients) or conventional laboratory SARS-CoV-2 PCR (conventional PCR, 6,189 patients) was performed.
Article Synopsis
- - Environmental variation plays a crucial role in the diversity of marine species like cunner, a temperate reef fish, yet there is limited understanding of how genomic and ecological factors shape their populations.
- - A comprehensive genome assembly of cunner revealed significant genetic variation across 803 individuals from 20 locations and indicated the existence of four regional population groups in the Northwest Atlantic.
- - Findings suggest that environmental factors, particularly benthic temperature and oxygen levels, influence genetic structure, providing valuable insights for the management and conservation of cunner in aquaculture and wild settings.
Article Synopsis
- * It compares various genetic marker panels (SSR and SNP) to measure the extent of European genetic influence in North American wild salmon, finding that a smaller set of SNPs can provide accurate estimates of admixture.
- * A custom SNP panel (301-SNP) and a Python package called salmoneuadmix were developed to streamline the monitoring of European admixture in salmon, showcasing the use of targeted genetics and machine learning for conservation efforts.
Deriving social determinants of health from underserved populations is an important step in the process of improving the well-being of these populations and in driving policy improvements to facilitate positive change in health outcomes. Collection, integration, and effective use of clinical data for this purpose presents a variety of specific challenges. We assert that combining expertise from three distinct domains, specifically, medical, statistical, and computer and data science can be applied along with provenance-aware, self-documenting workflow tools.
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