Publications by authors named "M Boti"
Identifying blood components influenced by rearing systems that serve as biomarkers to distinguish free-range from conventional broilers can improve animal health, welfare, and productivity. The current study aimed to evaluate specific blood parameters related to immune function and tissue stress, as biomarkers to differentiate free-range, slow-growing Sasso broilers from conventionally raised fast-growing Ross 308 broilers. For this purpose, serum IgM Natural Antibodies (NAbs) targeting actin and lipopolysaccharides (LPS) as key immunological parameters of natural immunity, along with creatine phosphokinase (CPK) and other significant stress and tissue-related biochemical parameters, were measured in a total of 300 broilers (150 per group) raised under industrial scale rearing systems, by standard methodology.
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- The study focused on patients with post-acute COVID-19 syndrome (PACS) who have cognitive complaints lasting over 8 weeks after infection.
- Researchers used a combination of neuropsychological tests, health questionnaires, blood samples, and MRI scans over several months to assess cognitive profiles and related biological and psychological factors.
- Results showed high prevalence of attention/executive function (69%) and verbal memory (39%) impairments, along with common issues like apathy (64%) and anxiety (57%), but cognitive evaluations remained stable over time despite no clear link to physical brain abnormalities or severe neuronal damage.
Objectives: To assess the feasibility and change in clinical outcomes associated with continuous glucose monitoring (CGM) use among a rural population in Malawi living with type 1 diabetes.
Design: A 2:1 open randomised controlled feasibility trial.
Setting: Two Partners In Health-supported Ministry of Health-run first-level district hospitals in Neno, Malawi.
Background: Phosphatase and tensin homolog, widely known as PTEN, is a major negative regulator of the PI3K/AKT/mTOR signaling pathway, involved in the regulation of a variety of important cellular processes, including cell proliferation, growth, survival, and metabolism. Since most of the molecules involved in this biological pathway have been described as key regulators in cancer, the study of the corresponding genes at several levels is crucial.
Objective: Although previous studies have elucidated the physiological role of PTEN under normal conditions and its involvement in carcinogenesis and cancer progression, the transcriptional profile of PTEN has been poorly investigated.