Pancreatic organogenesis mapped through space and time.

The spatial organization of cells within a tissue is dictated throughout dynamic developmental processes. We sought to understand whether cells geometrically coordinate with one another throughout development to achieve their organization. The pancreas is a complex cellular organ with a particular spatial organization.

Emerging spp. infections in Europe: characterization of human clinical isolates from German patients.

Bacteria of the genus are widely distributed in water bodies around the world. Some species have been identified as human pathogens causing intestinal and a variety of extraintestinal infections. In Germany, information on diseases caused by is rare, because infections are not notifiable in Germany.

SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2.

Human pluripotent stem cell-derived β-cells (SC-β-cells) represent an alternative cell source for transplantation in diabetic patients. Although mitogens could in theory be used to expand β-cells, adult β-cells very rarely replicate. In contrast, newly formed β-cells, including SC-β-cells, display higher proliferative capacity and distinct transcriptional and functional profiles.

subsp. serovar Paratyphi B from mute swan (): complete genome sequence features point towards invasive variant potential.

A subgroup of Salmonella (S.) enterica subsp. enterica serovar Paratyphi B is significantly associated with invasive infections in humans.

Draft genome sequence of a Shiga toxin-producing strain from deer meat showing an IS-element integration in the B-subunit of the Shiga toxin Stx2b gene.

Shiga toxin-producing (STEC) are important food-borne pathogens. Here we report sequence data of the STEC strain BfR-EC-18960, which has integrated IS elements in the B-subunit of the Shiga toxin Stx2b gene. The strain was isolated from deer meat at a local butchery in Germany in 2021.