Acta Inform Med
December 2016
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View Article and Find Full Text PDFImmunity is regulated by its signal molecules, interleukins, as well as by cellular contacts; however, in addition to these 'local' mechanisms there is also neuroendocrine regulation of the immune system, at the level of the organism as a whole that attunes the immunoreaction up or down. The systemic regulation is accomplished by nervous and endocrine signals that translate and transmit inputs from emotional, cognitive and associative processes in the brain. At the cellular level, neuroendocrine signals join local networks to influence biochemical processes in the cytoplasm and nuclei of the lymphocytes, macrophages and other cells of the immune system.
View Article and Find Full Text PDFThe involvement of iron and inflammation parameters on overall survival in non-small-cell lung cancer (NSCLC) patients was studied. Furthermore, transferrin receptors 1 (TfR1) and ferritin expression in tumor tissue, tumor stroma, and normal lung tissue were analyzed. Iron metabolism and inflammation parameters were determined by automated laboratory measurements at the time of diagnosis.
View Article and Find Full Text PDFInnate and acquired immune reactions are controlled by their intrinsic regulatory mechanisms, ie. by an array of cytokines that mediate communication among cells of the immune system itself and with other cells and tissues, e. g.
View Article and Find Full Text PDFBackground: The incidence of childhood tuberculosis as well as the number of children being in contact with persons having tuberculosis has increased in the region of Slavonski Brod during the past decade (1993-2003). The region is located in east Croatia along the border with Bosnia and close to the besieged and destroyed town of Vukovar. The region was heavily involved in recent military activities and migrations in Croatia and Bosnia (1991-1995).
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