Publications by authors named "M Bonovska"
Article Synopsis
- - The study analyzed 43 isolates from cattle in Bulgaria between 2015-2021 to assess the diversity of minisatellite VNTR loci, revealing the larger group was more diverse than the smaller group (HGI 0.67 vs. 0.60).
- - Six distinct clusters were identified, as well as nine orphans, with locus QUB3232 showing the highest discriminatory ability (HGI 0.64).
- - The research suggests using six specific loci for primary genotyping of the isolates in Bulgaria, indicating that simpler VNTR typing can be effective for monitoring bovine tuberculosis.
Background: This study aimed to characterize recent Mycobacterium bovis/M. caprae isolates from Bulgaria by whole-genome sequencing (WGS) to gain a first insight into their molecular diversity, transmission, and position within the global phylogeography of this important zoonotic species.
Results: The isolates were obtained from cattle in diverse locations of Bulgaria in 2015-2020 and were identified by microbiological and PCR assays.
Article Synopsis
- Bovine tuberculosis (bTB) poses a serious economic challenge in agriculture, especially in Bulgaria where infection rates have been increasing despite control efforts.
- A study analyzing 30 Mycobacterium bovis isolates used spoligotyping to identify strain diversity, revealing four distinct spoligotypes with differences in geographic prevalence across the country.
- This research highlighted the presence of M. caprae as a significant contributor to bTB in Bulgaria, marking the first detailed examination of the disease's phylogeography in the region.
PCR for detection of Mycobacterium tuberculosis in experimentally infected dogs.
J Vet Med B Infect Dis Vet Public Health
May 2005
The susceptibility of dogs to infection with Mycobacterium tuberculosis was studied through different ways of experimental infection. The examination shows, that in most cases the disease runs subclinically with pathological changes localized mainly in the lungs, lymph nodes, small intestines, liver, kidneys and spleen. Histological findings demonstrate granulomatous inflammation with caseosation and predominance of epitheloide macrophages and single lymphocytes.
View Article and Find Full Text PDFA study was carried out on the drug resistance as associated with the virulence of Staphylococcus aureus strains isolated from cows with endometritis. Hirota's method was employed to ascertain that resistance to penicillin, erythromycin, neomycin, and kanamycin was governed by plasmids. It was found at the same time that, fairly often, with the elimination of some of the resistant markers the virulence of the strain variants also dropped.
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