Publications by authors named "M Bonferroni"

Abnormal NIPT results, contrasting with normal fetus development, could disclose maternal malignancy, and this possibility should always be explained during pretest counseling. In this case, a complete diagnostic assessment is recommended and should be managed by a multidisciplinary team to define the best timing for diagnostic procedures, delivery, and treatment.

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Article Synopsis
  • Immunoglobulin M multiple myeloma and Waldenström macroglobulinemia are distinct but overlapping blood disorders characterized by the presence of immunoglobulin M monoclonal gammopathy.
  • Two cases highlight the importance of accurate diagnosis despite similar bone marrow presentation; one patient had multiple myeloma with different treatments compared to the other's diagnosis of Waldenström macroglobulinemia.
  • Differentiating between these conditions is crucial for appropriate treatment, emphasizing the need for thorough diagnostic evaluations, including cytogenetics and mutation testing.
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Several algorithms for early prediction of poor-mobilizing patients after chemotherapy and granulocyte colony-stimulating factor administration have been proposed. They generally define peripheral blood cut-off levels of CD34+ cells at a fixed day after starting chemotherapy, mostly with cyclophosphamide. To define an algorithm for early addition of plerixafor regardless of the chemotherapy regimen used, we retrospectively analyzed 280 chemomobilization attempts in 236 patients treated at our institution between 2002 and 2012.

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